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What is the correct way to bill an unlisted drug or biological?

When billing unlisted codes, the unit of service equals one and the following details must be entered into in Item 19 of the CMS-1500 or the electronic claim equivalent (Loop 2400/SV101-7):

  • Name of the drug
  • Dose administered (mg, cc, etc.)
  • Route of administration (IV, IM, SC, PO, etc.)
  • The invoice price (for new drugs if the WAC is unavailable, or for compounded drugs)

For additional information and guidance, visit Drugs and Biologicals – Coverage and Billing